Elevate bioprocessing with perfusion and intensification

Discover how eLAB TFF Single Use revolutionises perfusion and intensification of biotechnological processes. Optimise your bioprocesses with our effective and proven tool, improving productivity and efficiency in your lab.

Perfusion and Process Intensification with eLAB TFF SU

At TECNIC, we are proud to have our exceptional eLAB TFF Single UseĀ ā‡€ equipment. This lab equipment is transforming the way we intensify our biotechnological processes, boosting productivity and efficiency in our bioprocesses.

One of the most prominent examples of how eLAB TFF Single Use transforms our processes is through perfusion, a method of continuous culture intensification. In this method, cells are retained in or returned to the bioreactor, allowing higher product yields and higher cell concentrations to be obtained. This approach, which we have refined over time, also helps to reduce the workload and allows the exchange for a fresh medium that provides all the nutrients necessary for the proper maintenance of the cells. This is the value we have always offered at TECNIC: innovative and efficient solutions in biotechnology.

Innovation in process intensification eLAB TFF

At TECNIC, we choose to use our tangential filtration equipment with hollow fibre style filter technology and a low cell stress recirculation pump. This combination of cutting-edge technologies allows us to obtain high-density cell cultures while minimising the impact on cell viability and optimising the results of our bioprocesses.

Within our eLAB Bioreactor ā‡€ equipment, one of the ports is specially designed for perfusion. From this port, the low cell stress pump is connected, which sends the product to the hollow fibre filter. The cells retained in the filter are returned to the bioreactor, where a high cell density culture is obtained. The product filtered through the hollow fibre is connected to one of our integrated peristaltic pumps, allowing precise control of the constant flow of permeate, which is directed to a storage vessel.

The addition of fresh medium into the bioreactor is done via the overflow pump of the eLAB TFF unit, which is controlled based on the weight of the bioreactor. As the permeate is removed, fresh medium is added to maintain a constant weight in the bioreactor. In addition, our standard equipment has two integrated peristaltic pumps, one variable speed and one fixed speed, to control permeate flow and media addition.

At TECNIC, we are committed to excellence and innovation in the biotechnology industry. eLAB TFF Single Use represents our commitment to offer advanced solutions that optimise our bioprocesses and help us reach new levels of productivity and quality.

Do not miss the opportunity to improve your bioprocesses with eLAB TFF Single Use. Contact us for more information and to find out how our solution can benefit your biotech production.

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Rushton impeller

The Rushton impeller, also known as the flat disk impeller. It emerged as a solution to the challenges of mixing and oxygenation in the biotechnology industry. Its innovative design was quickly recognized for its exceptional ability to generate turbulent flow, making it a standard in the sector for decades.

Pitch blade impeller

This component is crucial for optimizing mixing and mass transfer in cell culture processes. Its specific design facilitates homogeneous distribution of nutrients and gases, essential for maintaining cell viability and growth under optimal conditions.

Rushton impeller

Characterized by its radial blades mounted perpendicularly to the shaft, the Rushton impeller is engineered to provide high shear rates and excellent gas dispersion, which is particularly effective in microbial. In biotechnological applications involving bacteria and yeast, the Rushton impeller excels by ensuring homogeneous mixing and optimal gas distribution, even in high-density cultures.

Cassette

We understand the importance of flexibility and efficiency in laboratory processes. That's why our equipment is designed to be compatible with Cassette filters, an advanced solution for a variety of filtration applications. Although we do not manufacture the filters directly, our systems are optimized to take full advantage of the benefits that Cassette filters offer.

Cassette filters are known for their high filtration capacity and efficiency in separation, making them ideal for ultrafiltration, microfiltration, and nanofiltration applications. By integrating these filters into our equipment, we facilitate faster and more effective processes, ensuring high-quality results.

Our equipment, being compatible with Cassette filters, offers greater versatility and adaptability. This means you can choose the filter that best suits your specific needs, ensuring that each experiment or production process is carried out with maximum efficiency and precision.

Moreover, our equipment stands out for its 100% automation capabilities. Utilizing advanced proportional valves, we ensure precise control over differential pressure, transmembrane pressure, and flow rate. This automation not only enhances the efficiency and accuracy of the filtration process but also significantly reduces manual intervention, making our systems highly reliable and user-friendly.

Hollow Fiber

We recognize the crucial role of flexibility and efficiency in laboratory processes. That's why our equipment is meticulously designed to be compatible with Hollow Fiber filters, providing an advanced solution for a broad spectrum of filtration applications. While we don't directly manufacture these filters, our systems are finely tuned to harness the full potential of Hollow Fiber filters.

Hollow Fiber filters are renowned for their exceptional performance in terms of filtration efficiency and capacity. They are particularly effective for applications requiring gentle handling of samples, such as in cell culture and sensitive biomolecular processes. By integrating these filters with our equipment, we enable more efficient, faster, and higher-quality filtration processes.

What sets our equipment apart is its 100% automation capability. Through the use of sophisticated proportional valves, our systems achieve meticulous control over differential pressure, transmembrane pressure, and flow rate. This level of automation not only boosts the efficiency and precision of the filtration process but also significantly diminishes the need for manual oversight, rendering our systems exceptionally reliable and user-friendly.

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